Halquinol CAS NO.8067-69-4

1) Description Yellowish-White to Yellowish grey voluminous powder, odour faint and characteristic of cresol. 2) Solubility Practically insoluble in water, soluble in 250 parts of ethanol (96%), in …

1) Description Yellowish-White to Yellowish grey voluminous powder, odour faint and characteristic of cresol. 2) Solubility Practically insoluble in water, soluble in 250 parts of ethanol (96%), in 130 parts of ether and 50 parts of chloroform. 3) Identification A) Burn 20 mg by the method for oxygen-flask combustion, using 5 ml of 2M sodium hydroxide as the absorbing liquid, and dilute to 25 ml with water. To 5 ml add 1 ml silver nitrate solution; a brown precipitate is produced. Add 5 ml of 5M ammonia, shake, filter and acidify the filtrate with nitric acid; a white precipitate is produced. B) To a suspension of 5 mg in 5 ml of water, add dropwise 5 % w/v solution of iron (III) chloride shaking after each addition; a pale bluishgreen colour is produced. 4) Acidity pH 3.0 to 5.0 (aqueous extract of 0.5 % chloroform solution). 5) Clarity 0.1 g in 100 ml chloroform should be clear. 6) Iron NMT 80 ppm 7) Chloride NMT 350 ppm 8) Sulfate NMT 300 ppm 9) Loss on drying NMT 0.5% 10) Sulphated ash NMT 0.2% 11) Assay(GC) 95 to 105 %5-Chloroquinoline-8-ol ------- 23 to 40 % 7-Chloroquinoline-8-ol ------- NMT 4 %5,7 Dichloroquinoline-8-ol --- 57 to 74 %