Methyl nicotinate CAS NO.93-60-7

1) Description White or almost white crystals or crystalline powder; characteristic odour. 2) Solubility Very soluble in water, in chloroform and in…

1) Description White or almost white crystals or crystalline powder; characteristic odour. 2) Solubility Very soluble in water, in chloroform and in ethanol (96%); freely soluble in ether. 3) Identification The infrared absorption spectrum is concordant with the reference spectrum of Methyl Nicotinate RS. The light absorption in the range 230 to 350 nm of a 0.002% w/v soln. exhibits maximum only at 264 nm. The absorbance at 264 nm is about 0.46. To 2 ml of a 0.1 % w/v solution add 6 ml of cyanogen bromide solution and 1 ml of 2.5 % v/v solution of aniline. A golden yellow colour is produced. 4) Related substances by TLC Impurity less than 0.5% by comparison of intensity of any secondary spot, if present. 5) Melting point 40 - 42 °C 6) Sulphated ash NMT 0.1% 7) Water NMT 0.5% w/w 8) ) Assay 99% - 101%